introduction

Granulosa cell tumours (GCT) are very rare malignant tumours of the ovaries. On average, they are diagnosed in 15-20 women a year in the Netherlands. The disease can occur at all ages, even in children. There is still too little knowledge about this type of cancer, which often prevents correct treatment.

symptoms and diagnosis

Patients usually have few symptoms. Sometimes there is abnormal vaginal bleeding. This is caused by the tumour producing oestrogen. As with other forms of ovarian cancer, the most common complaint is the presence of swelling in the abdomen. Often the diagnosis is made only after surgery, based on the final tissue examination. Although markers can be determined in the blood to suspect the diagnosis in advance (oestrogen, inhibin and AMH), granulosa cell tumour is often not suspected. This is unfortunate, as it is of utmost importance that the tumour is completely removed during surgery to minimise the risk of recurrence. Unfortunately, around 50% of women do develop a recurrence. The preferred treatment is to carry out more surgery.

Text: Prof. Ronald Zweemer, UMC Utrecht, for Olijfblad 2 – 2018 (March 2018)

the foundation

The aim of the Granulosa Cell Tumour Foundation is to raise awareness of this disease. We want to help stimulate and initiate research. We also want to strengthen communication between doctors and patients and amongst patients themselves. The aim of the foundation is formulated as follows:

• Empowering patients with granulosa cell tumours within the healthcare system;
• To work for a better and faster diagnostic pathway and to achieve better care and a higher quality of life for patients with granulosa cell tumour after their diagnosis;
• Fostering contact among peers;
• All the above both nationally and internationally and in the widest sense possible.